Angel2 Gene Summary [Mouse]
Predicted to enable mRNA 3'-UTR binding activity. Involved in mitochondrial mRNA 3'-end processing. Predicted to be located in Cajal body and cytoplasm. Orthologous to human ANGEL2 (angel homolog 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Angel2 |
| Official Name | angel homolog 2 [Source:MGI Symbol;Acc:MGI:1196310] |
| Ensembl ID | ENSMUSG00000026634 |
| Bio databases IDs | |
| Aliases | angel homolog 2 |
| Synonyms | 2610307I21Rik, 5730410O10Rik, AI845692, angel homolog 2, CCR4D, D1Ertd396e, D1Ertd654e, KIAA0759L, RGD1305056 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Angel2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein angel homolog 2 N-terminal
- mRNA 3' UTR binding
- Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
- Endonuclease/Exonuclease/phosphatase family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- Mitochondria
- mitochondrial matrix
- Cajal bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Angel2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- 3'-UTR-mediated mRNA stabilization
- negative regulation of mitotic cell cycle
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- Cajal body
Molecular Function
What the gene product does at the molecular level
- 3'-5'-exoribonuclease activity
- mRNA 3'-UTR binding