Mindy3 Gene Summary [Mouse]
Predicted to enable K48-linked deubiquitinase activity and cysteine-type deubiquitinase activity. Predicted to be involved in apoptotic process; protein K48-linked deubiquitination; and proteolysis. Predicted to be located in nuclear membrane and nucleoplasm. Is expressed in cranial ganglion; dorsal root ganglion; heart; neural retina; and telencephalon. Orthologous to human MINDY3 (MINDY lysine 48 deubiquitinase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Mindy3 |
| Official Name | MINDY lysine 48 deubiquitinase 3 [Source:MGI Symbol;Acc:MGI:1914210] |
| Ensembl ID | ENSMUSG00000026767 |
| Bio databases IDs | |
| Aliases | MINDY lysine 48 deubiquitinase 3 |
| Synonyms | 1810041E18Rik, 2310047O13RIK, 5830410F13Rik, C10orf97, CARP, DERP5, FAM188A, MINDY lysine 48 deubiquitinase 3, MST126, MSTP126, my042, RGD1309605 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mindy3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ubiquitin-specific protease
- enzyme
- protein binding
- Deubiquitinating enzyme MINDY-3/4, conserved domain
- ubiquitin-like-specific protease
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
- nuclear envelope
- synaptosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mindy3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- apoptotic process
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ubiquitin-specific protease activity
- protein binding