STRBP Gene Summary [Human]

Enables RNA binding activity. Predicted to be involved in spermatogenesis. Predicted to act upstream of or within mechanosensory behavior and spermatid development. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
STRBP
Official Name
spermatid perinuclear RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16462]
Ensembl ID
ENSG00000165209
Bio databases IDs NCBI: 55342 Ensembl: ENSG00000165209
Aliases spermatid perinuclear RNA binding protein
Synonyms 6430510M02RIK, C230082I21RIK, HEL162, ILF3L, p74, spermatid perinuclear RNA binding protein, SPNR
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STRBP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • DZF domain
  • microtubule binding
  • Double-stranded RNA binding motif
  • tubulin binding
  • double-stranded RNA binding motif (DSRM) superfamily
  • double-stranded RNA binding
  • protein binding
  • dsRNA-binding domain
  • single-stranded RNA binding

Pathways

Biological processes and signaling networks where the STRBP gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
  • non-insulin-dependent diabetes mellitus
regulated by
role in cell
  • function
  • development
  • motility

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • microtubule cytoskeleton
  • manchette
  • Nucleus
  • microtubules

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human STRBP gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mechanosensory behavior
  • cell motility
  • spermatid development

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • manchette

Molecular Function

What the gene product does at the molecular level
  • DNA binding
  • RNA binding
  • protein binding
  • double-stranded RNA binding
  • single-stranded RNA binding
  • microtubule binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.