Galk2 Gene Summary [Mouse]
Predicted to enable galactokinase activity. Predicted to be involved in galactose metabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; brain; cardiovascular system; ear; and genitourinary system. Orthologous to human GALK2 (galactokinase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Galk2 |
| Official Name | galactokinase 2 [Source:MGI Symbol;Acc:MGI:1917226] |
| Ensembl ID | ENSMUSG00000027207 |
| Bio databases IDs | |
| Aliases | galactokinase 2 |
| Synonyms | 2810017M24Rik, galactokinase 2, GK2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Galk2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- galactokinase
- Galactokinase galactose-binding signature
- GHMP kinases C terminal
- mevalonate kinase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- obesity
- lung carcinoma
- lung carcinoma process
- lung adenocarcinoma
- lung adenocarcinoma formation
- uterine leiomyoma
- leiomyomatosis
- gastroesophageal reflux
regulates
- BCL2L1
- carbohydrate
role in cell
- cell viability
- stabilization in
- stabilization
- alternative splicing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Galk2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- carbohydrate metabolic process
- galactose metabolic process
- carbohydrate phosphorylation
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- N-acetylgalactosamine kinase activity
- galactokinase activity