Zmat3 Gene Summary [Mouse]
Predicted to enable RNA binding activity and zinc ion binding activity. Predicted to be involved in positive regulation of apoptotic process. Predicted to act upstream of or within negative regulation of cell growth. Predicted to be located in nucleoplasm and plasma membrane. Is expressed in several structures, including early conceptus; genitourinary system; and heart. Orthologous to human ZMAT3 (zinc finger matrin-type 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zmat3 |
| Official Name | zinc finger matrin type 3 [Source:MGI Symbol;Acc:MGI:1195270] |
| Ensembl ID | ENSMUSG00000027663 |
| Bio databases IDs | |
| Aliases | zinc finger matrin type 3 |
| Synonyms | BC036485, PAG608, WIG-1, zinc finger matrin-type 3, zinc finger, matrin type 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zmat3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc-finger double-stranded RNA-binding
- nuclear localization sequence
- U1 zinc finger
- protein binding
- zinc finger domain
- Zinc-finger of C2H2 type
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- post-traumatic stress disorder
- pain
- depressive disorder
- papillary thyroid carcinoma
- papillary thyroid cancer
- refractive error
role in cell
- apoptosis
- expression in
- cell death
- growth
- transmembrane potential
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Plasma Membrane
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zmat3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- apoptotic process
- protein transport
- response to DNA damage stimulus
Cellular Component
Where in the cell the gene product is active
- nucleolus
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- RNA binding