Sh3d19 Gene Summary [Mouse]
Predicted to enable proline-rich region binding activity. Predicted to be involved in cytoskeleton organization; positive regulation of membrane protein ectodomain proteolysis; and regulation of cell morphogenesis. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Is expressed in gut; metanephros; metencephalon part of 4th ventricle choroid plexus; and olfactory epithelium. Orthologous to human SH3D19 (SH3 domain containing 19). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sh3d19 |
| Official Name | SH3 domain protein D19 [Source:MGI Symbol;Acc:MGI:1350923] |
| Ensembl ID | ENSMUSG00000028082 |
| Bio databases IDs | |
| Aliases | SH3 domain protein D19 |
| Synonyms | DKFZP434D0215, EBP, EVE-1, Kryn, LOC100361162, RGD1304885, SH3 domain containing 19, SH3 domain protein D19, SH3P19 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sh3d19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- proline-rich binding motif
- protein binding
- proline rich domain
- Src Homology 3 domain superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostatic carcinoma
- prostate cancer
- epithelial cancer
- COVID-19
- Hutchinson-Gilford progeria syndrome
- metabolic syndrome X
- asthma
role in cell
- morphogenesis
- organization
- transformation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cytosol
- nucleoplasm
- cell membrane leading edge
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sh3d19 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell morphogenesis
- cytoskeleton organization
- positive regulation of membrane protein ectodomain proteolysis
Cellular Component
Where in the cell the gene product is active
- cytosol
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding