Tead2

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in mesenchyme development and nervous system development. Acts upstream of or within several processes, including cellular response to retinoic acid; paraxial mesoderm development; and tube morphogenesis. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; embryo mesenchyme; and genitourinary system. Orthologous to human TEAD2 (TEA domain transcription factor 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tead2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Tead2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tead2 gene, providing context for its role in the cell.