Hp1bp3 Gene Summary [Mouse]
Predicted to enable DNA binding activity and nucleosome binding activity. Predicted to be involved in several processes, including cellular response to hypoxia; heterochromatin organization; and regulation of nucleus size. Predicted to be located in nuclear speck. Predicted to be part of nucleosome. Predicted to be active in chromosome and nucleus. Orthologous to human HP1BP3 (heterochromatin protein 1 binding protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hp1bp3 |
| Official Name | heterochromatin protein 1, binding protein 3 [Source:MGI Symbol;Acc:MGI:109369] |
| Ensembl ID | ENSMUSG00000028759 |
| Bio databases IDs | |
| Aliases | heterochromatin protein 1, binding protein 3 |
| Synonyms | heterochromatin protein 1 binding protein 3, heterochromatin protein 1, binding protein 3, HP1-BP74 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hp1bp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- linker histone H1 and H5 family
- binding protein
- H15
- chromatin binding
- protein binding
- DNA binding
Pathways
Biological processes and signaling networks where the Hp1bp3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromosome
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Hp1bp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of nucleus size
- heterochromatin organization
- regulation of transcription, DNA-dependent
- cellular response to hypoxia
- nucleosome assembly
- regulation of cell proliferation
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- chromosome
- nucleosome
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- nucleosome binding