Bcl7a Gene Summary [Mouse]
Acts upstream of or within motor behavior and neuron projection arborization. Part of SWI/SNF complex. Is expressed in several structures, including central nervous system; foregut; sensory organ; tooth; and vibrissa. Orthologous to human BCL7A (BAF chromatin remodeling complex subunit BCL7A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Bcl7a |
| Official Name | B cell CLL/lymphoma 7A [Source:MGI Symbol;Acc:MGI:1924295] |
| Ensembl ID | ENSMUSG00000029438 |
| Bio databases IDs | |
| Aliases | B cell CLL/lymphoma 7A |
| Synonyms | 4432415N06Rik, BAF chromatin remodeling complex subunit BCL7A, B cell CLL/lymphoma 7A, BCL7, SMARCJ1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bcl7a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- BCL7, N-terminal conserver region
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Huntington disease
- duodenal-type follicular lymphoma
- follicular non-Hodgkin disease
- duodenal cancer
- side effect
- venous thromboembolism
- non-Hodgkin disease
- non-Hodgkin lymphoma
- Burkitt lymphoma
- B-cell non-Hodgkin disease
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bcl7a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of mitotic metaphase/anaphase transition
- chromatin remodeling
- negative regulation of transcription, DNA-dependent
- negative regulation of cell differentiation
- positive regulation of cell proliferation
- regulation of G1/S transition of mitotic cell cycle
- positive regulation of double-strand break repair
- regulation of nucleotide-excision repair
- regulation of transcription from RNA polymerase II promoter
- regulation of G0 to G1 transition
Cellular Component
Where in the cell the gene product is active
- SWI/SNF complex
- chromatin
Molecular Function
What the gene product does at the molecular level
- protein binding