Radil Gene Summary [Mouse]

Predicted to enable GTPase binding activity. Predicted to be involved in neural crest cell migration and substrate adhesion-dependent cell spreading. Predicted to be part of protein-containing complex. Predicted to be active in microtubule. Is expressed in testis. Orthologous to human RADIL (Rap associating with DIL domain). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Radil
Official Name
Ras association and DIL domains [Source:MGI Symbol;Acc:MGI:2443088]
Ensembl ID
ENSMUSG00000029576
Bio databases IDs NCBI: 231858 Ensembl: ENSMUSG00000029576
Aliases Ras association and DIL domains
Synonyms D930005D10Rik, KIAA1849, Rap associating with DIL domain, Ras association and DIL domains, RASIP2, RGD1306155
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Radil often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain present in PSD-95, Dlg, and ZO-1/2
  • FHA domain
  • Ubl1_cv_Nsp3_N-like
  • canonical PDZ domain
  • Cargo binding domain of myosin 5 and similar proteins
  • protein binding
  • PDZ domain
  • forkhead associated (FHA) domain superfamily
  • DIL domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
regulated by
role in cell
  • proliferation
  • expression in
  • activation in
  • chemotaxis
  • adhesion
  • retraction
  • invasion by
  • number
  • elongation
  • retraction in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • microtubules

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Radil gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • neural crest cell migration
  • signal transduction
  • substrate adhesion-dependent cell spreading

Cellular Component

Where in the cell the gene product is active
  • macromolecular complex
  • microtubule

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • GTPase binding

Gene-Specific Assays for Results You Can Trust

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