RADIL Gene Summary [Human]
Predicted to enable GTPase binding activity. Acts upstream of or within substrate adhesion-dependent cell spreading. Located in microtubule. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | RADIL |
| Official Name | Rap associating with DIL domain [Source:HGNC Symbol;Acc:HGNC:22226] |
| Ensembl ID | ENSG00000157927 |
| Bio databases IDs | |
| Aliases | Rap associating with DIL domain |
| Synonyms | D930005D10Rik, KIAA1849, Rap associating with DIL domain, Ras association and DIL domains, RASIP2, RGD1306155 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RADIL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain present in PSD-95, Dlg, and ZO-1/2
- FHA domain
- Ubl1_cv_Nsp3_N-like
- canonical PDZ domain
- Cargo binding domain of myosin 5 and similar proteins
- protein binding
- PDZ domain
- forkhead associated (FHA) domain superfamily
- DIL domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RADIL gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neural crest cell migration
- signal transduction
- substrate adhesion-dependent cell spreading
Cellular Component
Where in the cell the gene product is active
- macromolecular complex
- microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding
- GTPase binding