Ptcd1 Gene Summary [Mouse]

Predicted to enable tRNA binding activity. Involved in mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Is expressed in central nervous system and sensory organ. Orthologous to human PTCD1 (pentatricopeptide repeat domain 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ptcd1
Official Name
pentatricopeptide repeat domain 1 [Source:MGI Symbol;Acc:MGI:1919049]
Ensembl ID
ENSMUSG00000029624
Bio databases IDs NCBI: 71799 Ensembl: ENSMUSG00000029624
Aliases pentatricopeptide repeat domain 1
Synonyms 1110069M14Rik, KIAA0632, pentatricopeptide repeat domain 1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ptcd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • tRNA binding
  • PPR repeat
  • Pentacotripeptide-repeat region of PRORP
  • pentatricopeptide repeat domain (PPR motif)
  • PPR repeat family
  • Pentatricopeptide repeat domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
regulated by
regulates
role in cell
  • autophagy in
  • glycolysis in
  • oxidative phosphorylation in
  • autophagy
  • activity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ptcd1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • tRNA 3'-end processing
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • tRNA binding

Gene-Specific Assays for Results You Can Trust

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