Tmcc1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including endosome fission; endosome membrane tubulation; and membrane fission. Predicted to be located in cytosol; endoplasmic reticulum-endosome membrane contact site; and rough endoplasmic reticulum. Predicted to be active in endomembrane system. Is expressed in nervous system and olfactory epithelium. Orthologous to human TMCC1 (transmembrane and coiled-coil domain family 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmcc1 |
| Official Name | transmembrane and coiled coil domains 1 [Source:MGI Symbol;Acc:MGI:2442368] |
| Ensembl ID | ENSMUSG00000030126 |
| Bio databases IDs | |
| Aliases | transmembrane and coiled coil domains 1 |
| Synonyms | 3632431M01Rik, KIAA0779, LOC100043425, LOC100048258, LOC100912698, mKIAA0779, RGD1311909, transmembrane and coiled-coil domain family 1, transmembrane and coiled coil domains 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmcc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Predicted transmembrane and coiled-coil 2 protein
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- cytosol
- rough endoplasmatic reticulum
- organelle membrane contact site
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmcc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane fission
- endosomal transport
- endoplasmic reticulum organization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- rough endoplasmic reticulum
- cytosol
- endomembrane system
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding