TMCC1 Gene Summary [Human]
Enables identical protein binding activity. Involved in several processes, including endosome fission; endosome membrane tubulation; and membrane fission. Located in cytosol; endoplasmic reticulum-endosome membrane contact site; and rough endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMCC1 |
| Official Name | transmembrane and coiled-coil domain family 1 [Source:HGNC Symbol;Acc:HGNC:29116] |
| Ensembl ID | ENSG00000172765 |
| Bio databases IDs | |
| Aliases | transmembrane and coiled-coil domain family 1 |
| Synonyms | 3632431M01Rik, KIAA0779, LOC100043425, LOC100048258, LOC100912698, mKIAA0779, RGD1311909, transmembrane and coiled-coil domain family 1, transmembrane and coiled coil domains 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMCC1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Predicted transmembrane and coiled-coil 2 protein
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- cytosol
- rough endoplasmatic reticulum
- organelle membrane contact site
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMCC1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane fission
- endosomal transport
- endoplasmic reticulum organization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- rough endoplasmic reticulum
- cytosol
- endomembrane system
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding