Cops7a Gene Summary [Mouse]

Predicted to be involved in protein deneddylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of COP9 signalosome. Is expressed in several structures, including adipose tissue; brain; eye; genitourinary system; and gut. Orthologous to human COPS7A (COP9 signalosome subunit 7A). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cops7a
Official Name
COP9 signalosome subunit 7A [Source:MGI Symbol;Acc:MGI:1349400]
Ensembl ID
ENSMUSG00000030127
Bio databases IDs NCBI: 26894 Ensembl: ENSMUSG00000030127
Aliases COP9 signalosome subunit 7A
Synonyms COP9 signalosome subunit 7A, CSN7, CSN7A, D6Ertd35e, SGN7a
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cops7a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
  • PCI domain
  • COP9 signalosome complex subunit 7a helix I domain
  • protein binding

Pathways

Biological processes and signaling networks where the Cops7a gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
regulated by
  • lipopolysaccharide
  • B lymphocytes
  • RYR1
  • TAFAZZIN
  • CST5
  • KRT19P3
role in cell
  • phosphorylation in
  • proliferation
  • ubiquitination in
  • homologous recombination in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cops7a gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein deneddylation
  • protein neddylation
  • signalosome assembly
  • regulation of protein neddylation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • cytosol
  • signalosome
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.