Erp27 Gene Summary [Mouse]
Predicted to be involved in protein folding and response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum. Is expressed in diencephalon lateral wall mantle layer and midbrain mantle layer. Orthologous to human ERP27 (endoplasmic reticulum protein 27). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Erp27 |
| Official Name | endoplasmic reticulum protein 27 [Source:MGI Symbol;Acc:MGI:1916437] |
| Ensembl ID | ENSMUSG00000030219 |
| Bio databases IDs | |
| Aliases | endoplasmic reticulum protein 27 |
| Synonyms | 1810033M07Rik, 1810047B09Rik, C12orf46, endoplasmic reticulum protein 27, PDIA8, RGD1565381 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Erp27 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- thioredoxin-like domain
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Erp27 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein folding
- response to unfolded protein
- response to endoplasmic reticulum stress
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum lumen
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein disulfide isomerase activity