Ddx3y Gene Summary [Mouse]

Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be involved in cell differentiation; gamete generation; and negative regulation of gene expression. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in P granule and nucleus. Is expressed in several structures, including heart; hemolymphoid system gland; liver; lung; and reproductive system. Orthologous to human DDX3Y (DEAD-box helicase 3 Y-linked). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ddx3y
Official Name
DEAD box helicase 3, Y-linked [Source:MGI Symbol;Acc:MGI:1349406]
Ensembl ID
ENSMUSG00000069045
Bio databases IDs NCBI: 26900 Ensembl: ENSMUSG00000069045
Aliases DEAD box helicase 3, Y-linked
Synonyms 8030469F12Rik, D1Pas1-rs1, Dby, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, DEAD box helicase 3, Y-linked
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ddx3y often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • DEAD/DEAH box helicase
  • Type III restriction enzyme, res subunit
  • helicase superfamily c-terminal domain
  • N-terminal helicase domain of the DEAD-box helicase superfamily
  • DEAD-like helicases superfamily
  • Helicase conserved C-terminal domain
  • P-loop containing Nucleoside Triphosphate Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetes mellitus
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • cytosol
  • nucleoplasm

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.