Slco1b2

Predicted to enable oligopeptide transmembrane transporter activity; organic anion transmembrane transporter activity; and prostaglandin transmembrane transporter activity. Acts upstream of or within several processes, including amide transport; bilirubin conjugation; and neuronal action potential. Predicted to be located in basal plasma membrane. Predicted to be active in basolateral plasma membrane. Is expressed in liver. Human ortholog(s) of this gene implicated in bilirubin metabolic disorder and gastrointestinal stromal tumor. Orthologous to human SLCO1B1 (solute carrier organic anion transporter family member 1B1); SLCO1B3 (solute carrier organic anion transporter family member 1B3); and SLCO1B7 (solute carrier organic anion transporter family member 1B7 (putative)). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slco1b2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Slco1b2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slco1b2 gene, providing context for its role in the cell.