Mphosph10 Gene Summary [Mouse]
Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in chromosome and nucleolus. Predicted to be part of Mpp10 complex and small-subunit processome. Is expressed in esophagus; lung; pituitary gland; urethra; and vertebral axis musculature. Orthologous to human MPHOSPH10 (M-phase phosphoprotein 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mphosph10 |
| Official Name | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) [Source:MGI Symbol;Acc:MGI:1915223] |
| Ensembl ID | ENSMUSG00000030521 |
| Bio databases IDs | |
| Aliases | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
| Synonyms | 2810453H10RIK, 5730405D16Rik, CT90, M-phase phosphoprotein 10, M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein), MPP10, MPP10P, PPP1R106 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mphosph10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mpp10 protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- pre-ribosome
- chromosome
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mphosph10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing, via transesterification reactions
- RNA splicing
- maturation of SSU-rRNA
- ribosomal small subunit biogenesis
- RNA processing
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- Mpp10 complex
- chromosome
- nucleolus
- small nucleolar ribonucleoprotein complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding