Dctn5 Gene Summary [Mouse]
Acts upstream of or within aorta development; coronary vasculature development; and ventricular septum development. Predicted to be located in centrosome; nuclear membrane; and nucleoplasm. Predicted to be part of dynactin complex. Is expressed in ganglia and metanephros. Orthologous to human DCTN5 (dynactin subunit 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dctn5 |
| Official Name | dynactin 5 [Source:MGI Symbol;Acc:MGI:1891689] |
| Ensembl ID | ENSMUSG00000030868 |
| Bio databases IDs | |
| Aliases | dynactin 5 |
| Synonyms | 4930427E12Rik, b2b315Clo, dynactin 5, dynactin subunit 5, MGC3248, RGD1305654 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dctn5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- LbetaH
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- centrosome
- cytosol
- nucleoplasm
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dctn5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- aorta development
- ventricular septum development
- coronary vasculature development
Cellular Component
Where in the cell the gene product is active
- centrosome
- nuclear membrane
- dynactin complex
- cytosol
- kinetochore
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding