Akip1 Gene Summary [Mouse]
Acts upstream of or within substrate adhesion-dependent cell spreading. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be active in nucleoplasm. Is expressed in genitourinary system; hippocampus; submandibular gland; and trachea. Orthologous to human AKIP1 (A-kinase interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Akip1 |
| Official Name | A kinase (PRKA) interacting protein 1 [Source:MGI Symbol;Acc:MGI:3041226] |
| Ensembl ID | ENSMUSG00000031023 |
| Bio databases IDs | |
| Aliases | A kinase (PRKA) interacting protein 1 |
| Synonyms | A-kinase interacting protein 1, BCA3, C11orf17, D7H11orf17, D930014E17Rik, ICRFP703B1614Q5.6, ORF27, RGD1306959 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Akip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
regulated by
- IL1B
- forskolin
- TP73
role in cell
- apoptosis
- expression in
- activation in
- phosphorylation in
- binding in
- growth
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- perinuclear region
- Mitochondria
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Akip1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- substrate adhesion-dependent cell spreading
Cellular Component
Where in the cell the gene product is active
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding