Akip1 Gene Summary [Rat]
Predicted to be involved in regulation of non-canonical NF-kappaB signal transduction. Predicted to act upstream of or within substrate adhesion-dependent cell spreading. Predicted to be active in nucleoplasm. Orthologous to human AKIP1 (A-kinase interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Akip1 |
| Official Name | A-kinase interacting protein 1 [Source:RGD Symbol;Acc:1306959] |
| Ensembl ID | ENSRNOG00000013744 |
| Bio databases IDs | |
| Aliases | A-kinase interacting protein 1 |
| Synonyms | A-kinase interacting protein 1, BCA3, C11orf17, D7H11orf17, D930014E17Rik, ICRFP703B1614Q5.6, ORF27, RGD1306959 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Akip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
role in cell
- apoptosis
- expression in
- activation in
- phosphorylation in
- binding in
- growth
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- perinuclear region
- Mitochondria
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Akip1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- substrate adhesion-dependent cell spreading
Cellular Component
Where in the cell the gene product is active
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding