Dcps Gene Summary [Mouse]
Predicted to enable 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity; RNA 7-methylguanosine cap binding activity; and identical protein binding activity. Predicted to be involved in deadenylation-dependent decapping of nuclear-transcribed mRNA and mRNA cis splicing, via spliceosome. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be active in P-body and nucleus. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; nervous system; and sensory organ. Orthologous to human DCPS (decapping enzyme, scavenger). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dcps |
| Official Name | decapping enzyme, scavenger [Source:MGI Symbol;Acc:MGI:1916555] |
| Ensembl ID | ENSMUSG00000032040 |
| Bio databases IDs | |
| Aliases | decapping enzyme, scavenger |
| Synonyms | 1700001E16Rik, ARS, DCS-1, decapping enzyme, scavenger, HINT-5, HSL1, HSPC015 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dcps often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA 7-methylguanosine cap binding
- exoribonuclease
- pyrophosphatase
- enzyme
- protein binding
- Scavenger mRNA decapping enzyme (DcpS) N-terminal
- identical protein binding
- Scavenger mRNA decapping enzyme C-term binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- perinuclear region
- Mitochondria
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dcps gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA cis splicing, via spliceosome
- deadenylation-dependent decapping of nuclear-transcribed mRNA
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- mitochondrion
- cytosol
- cytoplasmic mRNA processing body
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- RNA 7-methylguanosine cap binding
- protein binding
- exoribonuclease activity