Lactb Gene Summary [Mouse]
Predicted to enable identical protein binding activity and peptidase activity. Predicted to be involved in proteolysis and regulation of lipid metabolic process. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human LACTB (lactamase beta). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lactb |
| Official Name | lactamase, beta [Source:MGI Symbol;Acc:MGI:1933395] |
| Ensembl ID | ENSMUSG00000032370 |
| Bio databases IDs | |
| Aliases | lactamase, beta |
| Synonyms | G24, LACT-1, lactamase beta, lactamase, beta, lactamase β, lactamase, β, MRPL56, β Lactamase |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lactb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Penicillin binding protein transpeptidase domain
- beta-lactamase
- peptidase
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- age-related macular degeneration
- prostate cancer
- mucinous ovarian carcinoma
- mucinous ovarian cancer
- gastric cancer
- serous ovarian adenocarcinoma
- serous ovarian cancer
- ovarian neoplasia
- obesity
role in cell
- expression in
- growth
- proliferation
- differentiation
- autophagy in
- formation by
- epithelial-mesenchymal transition
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
- microsome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lactb gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- lipid metabolic process
- regulation of lipid metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- peptidase activity