Plscr4 Gene Summary [Mouse]
Predicted to enable CD4 receptor binding activity; enzyme binding activity; and phospholipid scramblase activity. Involved in cellular response to lipopolysaccharide. Predicted to be located in nucleus. Predicted to be active in plasma membrane. Is expressed in esophagus. Orthologous to human PLSCR4 (phospholipid scramblase 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Plscr4 |
| Official Name | phospholipid scramblase 4 [Source:MGI Symbol;Acc:MGI:2143267] |
| Ensembl ID | ENSMUSG00000032377 |
| Bio databases IDs | |
| Aliases | phospholipid scramblase 4 |
| Synonyms | phospholipid scramblase 4, Pls4, TRA1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Plscr4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipid scramblase
- enzyme binding
- enzyme
- protein binding
- zDHHC ankyrin repeat binding domain
- LURP-one-related
- CD4 receptor binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Plscr4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to lipopolysaccharide
- phospholipid scrambling
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding
- CD4 receptor binding
- SH3 domain binding
- enzyme binding
- phospholipid scramblase activity