Ttc21a

Involved in flagellated sperm motility and spermatid development. Predicted to be part of intraciliary transport particle A. Is expressed in 4th ventricle; choroid plexus; lateral ventricle choroid plexus; and olfactory epithelium. Human ortholog(s) of this gene implicated in spermatogenic failure 37. Orthologous to human TTC21A (tetratricopeptide repeat domain 21A). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ttc21a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ttc21a gene, providing context for its role in the cell.