Nol12 Gene Summary [Mouse]

Predicted to enable identical protein binding activity; rRNA binding activity; and single-stranded DNA binding activity. Located in nucleolus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human NOL12 (nucleolar protein 12). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nol12
Official Name
nucleolar protein 12 [Source:MGI Symbol;Acc:MGI:2146285]
Ensembl ID
ENSMUSG00000033099
Bio databases IDs NCBI: 97961 Ensembl: ENSMUSG00000033099
Aliases nucleolar protein 12
Synonyms dJ37E16.7, MGC3731, Nop25, nucleolar protein 12, RGD1305327
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nol12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • rRNA binding
  • single-stranded DNA binding
  • protein binding
  • identical protein binding
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Nol12 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • nucleolus

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • RNA binding
  • protein binding
  • rRNA binding
  • single-stranded DNA binding

Gene-Specific Assays for Results You Can Trust

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