Cog7 Gene Summary [Mouse]
Predicted to be involved in several processes, including Golgi vesicle transport; protein localization to Golgi apparatus; and protein stabilization. Predicted to be located in Golgi apparatus and nucleolus. Predicted to be part of Golgi transport complex. Is expressed in lung; metanephros; pancreas; submandibular gland; and testis. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIe. Orthologous to human COG7 (component of oligomeric golgi complex 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Cog7 |
| Official Name | component of oligomeric golgi complex 7 [Source:MGI Symbol;Acc:MGI:2685013] |
| Ensembl ID | ENSMUSG00000034951 |
| Bio databases IDs | |
| Aliases | component of oligomeric golgi complex 7 |
| Synonyms | 5630400E24, 5630400E24Rik, CDG2E, component of oligomeric golgi complex 7, Gm167 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cog7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Golgi complex component 7 (COG7)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- perinuclear Golgi regions
- Golgi Apparatus
- Golgi membrane
- trans Golgi network
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cog7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycosylation
- protein localization in Golgi apparatus
- retrograde vesicle-mediated transport, Golgi to ER
- Golgi organization
- protein glycosylation
- protein localization to organelle
- intracellular protein transport
- protein stabilization
- retrograde transport, vesicle recycling within Golgi
Cellular Component
Where in the cell the gene product is active
- Golgi transport complex
- intracellular membrane-bounded organelle
- Golgi apparatus
- Golgi membrane
- nucleolus
- trans-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- protein binding