Gosr1 Gene Summary [Mouse]
Predicted to enable SNAP receptor activity. Predicted to be involved in Golgi vesicle transport; retrograde transport, endosome to Golgi; and vesicle fusion. Located in Golgi membrane. Orthologous to human GOSR1 (golgi SNAP receptor complex member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gosr1 |
| Official Name | golgi SNAP receptor complex member 1 [Source:MGI Symbol;Acc:MGI:1858260] |
| Ensembl ID | ENSMUSG00000010392 |
| Bio databases IDs | |
| Aliases | golgi SNAP receptor complex member 1 |
| Synonyms | AI414660, golgi SNAP receptor complex member 1, GOLIM2, GOS-28, GOS28/P28, GOSRI, GS28, P28 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gosr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SNAP receptor
- cytoplasmic domain
- Snare region anchored in the vesicle membrane C-terminus
- protein binding
- SNARE motif
- transporter
Pathways
Biological processes and signaling networks where the Gosr1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi-enriched fraction
- membrane fraction
- Golgi-intermediate compartment membrane fractions
- perinuclear Golgi regions
- perinuclear region
- cellular membrane
- Golgi Apparatus
- Golgi membrane
- cis Golgi networks
- transport vesicles
- microsomal membrane
- Golgi cisternae
- Golgi vesicles
- cis Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gosr1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ER to Golgi vesicle-mediated transport
- vesicle fusion
- protein transport
- intra-Golgi vesicle-mediated transport
- retrograde transport, endosome to Golgi
- inter-Golgi cisterna vesicle-mediated transport
Cellular Component
Where in the cell the gene product is active
- cis-Golgi network
- membrane
- SNARE complex
- cytosol
- Golgi apparatus
- Golgi membrane
- transport vesicle
- Golgi medial cisterna
Molecular Function
What the gene product does at the molecular level
- SNAP receptor activity