Ccl7

Enables CCR2 chemokine receptor binding activity. Predicted to be involved in several processes, including cellular response to ethanol; eosinophil chemotaxis; and positive regulation of natural killer cell chemotaxis. Located in extracellular space. Is expressed in several structures, including central nervous system; leg; lung; retina; and vertebral axis musculature. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human CCL7 (C-C motif chemokine ligand 7). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccl7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ccl7 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.