Ccl7

Predicted to enable CCR1 chemokine receptor binding activity; CCR2 chemokine receptor binding activity; and chemokine activity. Involved in cellular response to ethanol and response to gamma radiation. Predicted to be active in extracellular space. Used to study glomerulonephritis. Biomarker of bronchiolitis obliterans; interstitial nephritis; nephrosis; and silicosis. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human CCL7 (C-C motif chemokine ligand 7). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ccl7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ccl7 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.