Mbnl3 Gene Summary [Mouse]
Predicted to enable RNA binding activity. Acts upstream of or within negative regulation of myoblast differentiation. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in several structures, including 1st branchial arch; early conceptus; future brain; genitourinary system; and hemolymphoid system gland. Orthologous to human MBNL3 (muscleblind like splicing regulator 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mbnl3 |
| Official Name | muscleblind like splicing factor 3 [Source:MGI Symbol;Acc:MGI:2444912] |
| Ensembl ID | ENSMUSG00000036109 |
| Bio databases IDs | |
| Aliases | muscleblind like splicing factor 3 |
| Synonyms | A530038J18Rik, AI661274, CHCR, E430034C16Rik, LOC100132018, MBLX, MBLX39, MBXL, muscleblind like splicing factor 3, muscleblind-like splicing regulator 3, RGD1565834 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mbnl3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc finger
- CCCH-type zinc finger
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- protein binding
- zinc finger domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mbnl3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- negative regulation of myoblast differentiation
- regulation of RNA splicing
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- metal ion binding