Noa1 Gene Summary [Mouse]
Predicted to enable GTP binding activity. Involved in mitochondrial ribosome assembly. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; nervous system; and skeleton. Orthologous to human NOA1 (nitric oxide associated 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Noa1 |
| Official Name | nitric oxide associated 1 [Source:MGI Symbol;Acc:MGI:1914306] |
| Ensembl ID | ENSMUSG00000036285 |
| Bio databases IDs | |
| Aliases | nitric oxide associated 1 |
| Synonyms | 2610024G14Rik, AtNOS1, C4orf14, hAtNOS1, hNOA1, mAtNOS1, MTG3, nitric oxide associated 1, RGD1359460 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Noa1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- ribosome biogenesis GTPase YqeH
- protein binding
- Circularly permuted YlqF-related GTPases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- coronary artery disease
- growth failure
regulated by
- C2C12 cells
regulates
- oxygen
- superoxide
- Mitochondrial complex 1/3
- TXN2
role in cell
- cell death
- apoptosis
- production in
- organization
- abnormal morphology
- function
- consumption in
- oxidation in
- shape
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Noa1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- apoptotic process
- mitochondrion organization
Cellular Component
Where in the cell the gene product is active
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- GTP binding
- RNA binding
- protein binding