P2ry14 Gene Summary [Mouse]
Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in plasma membrane. Orthologous to human P2RY14 (purinergic receptor P2Y14). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | P2ry14 |
| Official Name | purinergic receptor P2Y, G-protein coupled, 14 [Source:MGI Symbol;Acc:MGI:2155705] |
| Ensembl ID | ENSMUSG00000036381 |
| Bio databases IDs | |
| Aliases | purinergic receptor P2Y, G-protein coupled, 14 |
| Synonyms | A330108O13Rik, BPR105, GPR105, P2Y14, purinergic receptor P2Y14, purinergic receptor P2Y, G-protein coupled, 14, UDP-glucose receptor |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse P2ry14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Cholecystokinin A receptor, N-terminal
- 7 transmembrane receptor (rhodopsin family)
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the P2ry14 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- androgenic alopecia
- insomnia
- primary gout
- uterine serous papillary cancer
- impaired glucose tolerance
- COVID-19
role in cell
- growth
- expression in
- phosphorylation in
- apoptosis
- activation in
- formation
- NETosis
- cellular infiltration by
- cisplatin sensitivity
- homeostasis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse P2ry14 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
- G-protein coupled purinergic nucleotide receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled purinergic nucleotide receptor activity
- UDP-activated nucleotide receptor activity