Tbcc Gene Summary [Mouse]
Predicted to enable GTPase activity. Predicted to be involved in post-chaperonin tubulin folding pathway and tubulin complex assembly. Predicted to be located in cytosol and photoreceptor connecting cilium. Predicted to be active in cytoplasm. Is expressed in Meckel's cartilage; autopod; and skeleton. Orthologous to human TBCC (tubulin folding cofactor C). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tbcc |
| Official Name | tubulin-specific chaperone C [Source:MGI Symbol;Acc:MGI:1919976] |
| Ensembl ID | ENSMUSG00000036430 |
| Bio databases IDs | |
| Aliases | tubulin-specific chaperone C |
| Synonyms | 2810055C19Rik, CFC, tubulin folding cofactor C, tubulin-specific chaperone C |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tbcc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tubulin-specific chaperone C N-terminal domain
- GTPase
- Tubulin binding cofactor C
- enzyme
- protein binding
- chaperone binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoskeleton
- Endoplasmic Reticulum
- microtubules
- cytosol
- connecting cilia
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tbcc gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tubulin complex assembly
- post-chaperonin tubulin folding pathway
- protein folding
Cellular Component
Where in the cell the gene product is active
- photoreceptor connecting cilium
- cytoskeleton
- cytoplasm
- cytosol
- microtubule
Molecular Function
What the gene product does at the molecular level
- tubulin binding
- protein binding
- GTPase activity
- chaperone binding