Kin Gene Summary [Mouse]
Enables double-stranded DNA binding activity. Involved in DNA damage response and DNA replication. Located in nucleus. Is expressed in several structures, including branchial arch; cerebral cortex; inner ear; limb; and midgut. Orthologous to human KIN (Kin17 DNA and RNA binding protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kin |
| Official Name | Kin17 DNA and RNA binding protein [Source:MGI Symbol;Acc:MGI:96676] |
| Ensembl ID | ENSMUSG00000037262 |
| Bio databases IDs | |
| Aliases | Kin17 DNA and RNA binding protein |
| Synonyms | BTCD, KIN17, Kin17 DNA and RNA binding protein, LOC683353, Rts2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kin often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 6-pyruvoyl-tetrahydropterin synthase related domain (membrane protein)
- double-stranded DNA binding
- U1 zinc finger
- protein binding
- Zinc-finger of C2H2 type
- Domain of Kin17 curved DNA-binding protein
- DNA binding
- KN17 SH3-like C-terminal domain
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- intracellular membrane-bounded organelle
- cytosol
- nuclear foci
- nucleoplasm
- nuclear matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kin gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA repair
- DNA replication
- DNA recombination
- mRNA processing
- response to DNA damage stimulus
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- intracellular membrane-bounded organelle
- nuclear matrix
- macromolecular complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- RNA binding
- metal ion binding
- double-stranded DNA binding