N4bp2 Gene Summary [Mouse]
Predicted to enable ATP binding activity; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; and DNA endonuclease activity. Located in cytosol. Is expressed in ovary and primary sex cord. Orthologous to human N4BP2 (NEDD4 binding protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | N4bp2 |
| Official Name | NEDD4 binding protein 2 [Source:MGI Symbol;Acc:MGI:2684414] |
| Ensembl ID | ENSMUSG00000037795 |
| Bio databases IDs | |
| Aliases | NEDD4 binding protein 2 |
| Synonyms | B3BP, E430014I16, Gm1791, Gm868, LOC100507659, NEDD4 binding protein 2, RGD1565738 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse N4bp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Small MutS-related domain
- UBA domain-like superfamily
- endonuclease
- Smr domain
- Domain of unknown function (DUF1771)
- ATP-binding domain
- ATP binding
- enzyme
- protein binding
- polynucleotide 5'-hydroxyl-kinase
- AAA domain
- polynucleotide kinase domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse N4bp2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA metabolic process
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- ubiquitin binding
- endonuclease activity
- endodeoxyribonuclease activity
- ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity