Gngt2 Gene Summary [Mouse]
Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Is expressed in brown fat; retina; retina outer nuclear layer; and thymus primordium. Orthologous to human GNGT2 (G protein subunit gamma transducin 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gngt2 |
| Official Name | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 [Source:MGI Symbol;Acc:MGI:893584] |
| Ensembl ID | ENSMUSG00000038811 |
| Bio databases IDs | |
| Aliases | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 |
| Synonyms | Cone t gamma, Cone t γ, G-GAMMA-8, G-GAMMA-C, GNG9, GNGT8, G protein subunit gamma transducin 2, G protein subunit γ transducin 2, guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2, guanine nucleotide binding protein (G protein), γ transducing activity polypeptide 2, G-γ-8, G-γ-C, HG3I, LOC688154 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gngt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GGL
- GTPase
- enzyme
- GGL domain
Pathways
Biological processes and signaling networks where the Gngt2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- Golgi Apparatus
- cone outer segments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gngt2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- G-protein coupled receptor signaling pathway
- phototransduction
Cellular Component
Where in the cell the gene product is active
- heterotrimeric G-protein complex
Molecular Function
What the gene product does at the molecular level
- G-protein beta-subunit binding
- GTPase activity