Shd Gene Summary [Mouse]

Predicted to enable phosphotyrosine residue binding activity. Orthologous to human SHD (Src homology 2 domain containing transforming protein D). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Shd
Official Name
src homology 2 domain-containing transforming protein D [Source:MGI Symbol;Acc:MGI:1099461]
Ensembl ID
ENSMUSG00000039154
Bio databases IDs NCBI: 20420 Ensembl: ENSMUSG00000039154
Aliases src homology 2 domain-containing transforming protein D
Synonyms Src homology 2 domain containing transforming protein D
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Shd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Src homology 2 (SH2) domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
regulated by
role in cell
  • cell death
  • cell viability
  • colony survival
  • necroptosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Shd gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • phosphotyrosine binding
  • protein binding