Cdh26 Gene Summary [Mouse]

Predicted to enable several functions, including alpha-catenin binding activity; beta-catenin binding activity; and cell adhesion molecule binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and cell-cell junction organization. Predicted to be located in microtubule cytoskeleton and plasma membrane. Predicted to be part of catenin complex. Predicted to be active in adherens junction. Is expressed in brain; gut; male reproductive gland or organ; and retina. Orthologous to human CDH26 (cadherin 26). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cdh26
Official Name
cadherin-like 26 [Source:MGI Symbol;Acc:MGI:2685856]
Ensembl ID
ENSMUSG00000039155
Bio databases IDs NCBI: 381409 Ensembl: ENSMUSG00000039155
Aliases cadherin-like 26
Synonyms cadherin 26, cadherin-like 26, Gm1010, VR20
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cdh26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • alpha-catenin binding
  • beta-catenin binding
  • integrin binding
  • Cadherin repeat-like domain
  • protein binding

Pathways

Biological processes and signaling networks where the Cdh26 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • rheumatoid arthritis
  • eosinophilic esophagitis
  • post-operative acute kidney injury
regulated by
role in cell
  • activation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • microtubule cytoskeleton
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cdh26 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • calcium-dependent cell-cell adhesion
  • adherens junction organization
  • cell-cell junction assembly
  • multicellular organismal development
  • cell morphogenesis
  • cell-cell adhesion mediated by cadherin
  • homophilic cell adhesion
  • cell migration
  • CD4-positive, alpha-beta T cell activation

Cellular Component

Where in the cell the gene product is active
  • adherens junction
  • microtubule cytoskeleton
  • catenin complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • alpha-catenin binding
  • delta-catenin binding
  • protein binding
  • cadherin binding
  • calcium ion binding
  • integrin binding
  • beta-catenin binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.