Lrrc17 Gene Summary [Mouse]
Involved in bone marrow development and negative regulation of osteoclast differentiation. Located in extracellular space. Is expressed in early conceptus; eye; and ovary. Orthologous to human LRRC17 (leucine rich repeat containing 17). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Lrrc17 |
| Official Name | leucine rich repeat containing 17 [Source:MGI Symbol;Acc:MGI:1921761] |
| Ensembl ID | ENSMUSG00000039883 |
| Bio databases IDs | |
| Aliases | leucine rich repeat containing 17 |
| Synonyms | 4833425M04Rik, 6130400C22Rik, leucine rich repeat containing 17, P37NB |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lrrc17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase 1 regulatory subunit 42
- Leucine rich repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lrrc17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of osteoclast differentiation
- osteoblast proliferation
- osteoblast differentiation
- bone marrow development
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular matrix