Gemin8 Gene Summary [Mouse]

Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in cytosol and nucleus. Predicted to be part of SMN complex. Is expressed in submandibular gland primordium. Orthologous to human GEMIN8 (gem nuclear organelle associated protein 8). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gemin8
Official Name
gem nuclear organelle associated protein 8 [Source:MGI Symbol;Acc:MGI:2384300]
Ensembl ID
ENSMUSG00000040621
Bio databases IDs NCBI: 237221 Ensembl: ENSMUSG00000040621
Aliases gem nuclear organelle associated protein 8
Synonyms B130034M20RIK, B930082C09Rik, FAM51A1, gem (nuclear organelle) associated protein 8, gem nuclear organelle associated protein 8, LOC105373138
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gemin8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Gemini of Cajal bodies-associated protein 8
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • snRNP

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gemin8 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spliceosomal snRNP assembly

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • SMN-Sm protein complex
  • cytosol
  • SMN complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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