Rcsd1 Gene Summary [Mouse]
Predicted to enable actin filament binding activity; phosphatidylinositol phosphate binding activity; and retromer complex binding activity. Predicted to be involved in several processes, including cellular hyperosmotic response; protein localization to endosome; and retrograde transport, endosome to Golgi. Predicted to be part of WASH complex. Predicted to be active in early endosome. Is expressed in several structures, including blood; chondrocranium; gut; meninges; and metanephros. Orthologous to human RCSD1 (RCSD domain containing 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rcsd1 |
| Official Name | RCSD domain containing 1 [Source:MGI Symbol;Acc:MGI:2676394] |
| Ensembl ID | ENSMUSG00000040723 |
| Bio databases IDs | |
| Aliases | RCSD domain containing 1 |
| Synonyms | A430105K13RIK, CAPZIP, Gm19627, LOC105371602, MGC21854, MK2S4, RCSD domain containing 1, RGD1304715 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rcsd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- actin filament binding
- RCSD region
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostate cancer
- invasive breast carcinoma
- breast carcinoma
- invasive breast cancer
- liver cancer
- epithelial cancer
- survival
- prostatic adenocarcinoma
- hepatocellular carcinoma
- chromophobe renal cell carcinoma
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rcsd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- skeletal muscle contraction
- protein localization in endosome
- cellular hyperosmotic response
- retrograde transport, endosome to Golgi
Cellular Component
Where in the cell the gene product is active
- early endosome
- cytosol
- WASH complex
- actin filament
Molecular Function
What the gene product does at the molecular level
- actin filament binding