Slc39a11 Gene Summary [Mouse]
Enables copper ion transmembrane transporter activity and zinc ion transmembrane transporter activity. Involved in zinc ion import across plasma membrane. Located in Golgi apparatus; nucleus; and plasma membrane. Orthologous to human SLC39A11 (solute carrier family 39 member 11). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc39a11 |
| Official Name | solute carrier family 39 (metal ion transporter), member 11 [Source:MGI Symbol;Acc:MGI:1917056] |
| Ensembl ID | ENSMUSG00000041654 |
| Bio databases IDs | |
| Aliases | solute carrier family 39 (metal ion transporter), member 11 |
| Synonyms | 1810074D23RIK, C17orf26, solute carrier family 39 member 11, solute carrier family 39, member 11, solute carrier family 39 (metal ion transporter), member 11, ZIP-11 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc39a11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- copper ion transporter
- ZIP Zinc transporter
- zinc ion transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostate cancer
- non-insulin-dependent diabetes mellitus
- inflammatory bowel disease
- COVID-19
- acute myeloid leukemia
- amyotrophic lateral sclerosis
- spontaneous preterm birth
- ulcerative colitis
- diverticular disease
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Plasma Membrane
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc39a11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- zinc ion import
- zinc ion transmembrane transport
- copper ion transmembrane transport
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- membrane
- Golgi apparatus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- zinc ion transmembrane transporter activity
- copper ion transmembrane transporter activity