Rasl12 Gene Summary [Mouse]

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be active in plasma membrane. Orthologous to human RASL12 (RAS like family 12). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Rasl12
Official Name
RAS-like, family 12 [Source:MGI Symbol;Acc:MGI:1918034]
Ensembl ID
ENSMUSG00000041696
Bio databases IDs NCBI: 70784 Ensembl: ENSMUSG00000041696
Aliases RAS-like, family 12
Synonyms 4631404I11RIK, RAS like family 12, RAS-like, family 12, RIS
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rasl12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • small GTP-binding protein domain
  • Small GTPase of the Ras superfamily (ill-defined subfamily)
  • Ras family
  • Rab subfamily of small GTPases
  • enzyme
  • protein binding
  • pseudoGTPase domain found in the family of p190RhoGAP
  • Ras of Complex, Roc, domain of DAPkinase
  • Rho (Ras homology) subfamily of Ras-like small GTPases
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • Ras subfamily of RAS small GTPases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hypertension
  • Huntington disease
  • preeclampsia
  • endometrial cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rasl12 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • protein binding
  • GTPase activity
  • small monomeric GTPase activity
  • GDP binding

Gene-Specific Assays for Results You Can Trust

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