Wdr41 Gene Summary [Mouse]

This gene encodes a protein of unknown function, but which contains a WD40 domain consisting of six WD40 repeats. The WD40 domain is one of the most abundant protein domains in eukaryotes, and is found in proteins with widely varying cellular functions. However, proteins with this domain often provide a rigid scaffold for protein-protein interactions. [provided by RefSeq, Aug 2012]

Details

Type
Protein Coding
Official Symbol
Wdr41
Official Name
WD repeat domain 41 [Source:MGI Symbol;Acc:MGI:2445123]
Ensembl ID
ENSMUSG00000042015
Bio databases IDs NCBI: 218460 Ensembl: ENSMUSG00000042015
Aliases WD repeat domain 41
Synonyms B830029I03Rik, MSTP048, WD repeat domain 41
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr41 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • WD40 repeats
  • guanyl-nucleotide exchange factor
  • WD domain, G-beta repeat
  • WD40
  • GTPase activator
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast adenocarcinoma
  • Parkinson disease
  • Alzheimer disease
  • dextran sodium sulfate-induced colitis
regulated by
role in cell
  • production in
  • autophagy by
  • recruitment in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr41 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • autophagy
  • regulation of autophagy
  • negative regulation of immune response
  • positive regulation of GTPase activity
  • negative regulation of exocytosis

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • guanyl-nucleotide exchange factor complex
  • lysosomal membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • guanyl-nucleotide exchange factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.