Upk3b Gene Summary [Mouse]
Involved in negative regulation of D-glucose import. Predicted to be located in plasma membrane. Predicted to be active in membrane. Is expressed in heart; intraembryonic coelom; proepicardium; and urinary system. Orthologous to human UPK3B (uroplakin 3B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Upk3b |
| Official Name | uroplakin 3B [Source:MGI Symbol;Acc:MGI:2140882] |
| Ensembl ID | ENSMUSG00000042985 |
| Bio databases IDs | |
| Aliases | uroplakin 3B |
| Synonyms | P35, PMS2L14, RGD1309615, UP3B, UPIIIB, uroplakin 3B |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Upk3b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Uroplakin IIIb, IIIa and II
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Upk3b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of gene expression
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane