Gimap5 Gene Summary [Mouse]
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | Gimap5 |
| Official Name | GTPase, IMAP family member 5 [Source:MGI Symbol;Acc:MGI:2442232] |
| Ensembl ID | ENSMUSG00000043505 |
| Bio databases IDs | |
| Aliases | GTPase, IMAP family member 5 |
| Synonyms | 2010110D23Rik, D630024P16, E230026N22Rik, Gimap3, Gimap5, GTPase, IMAP family member 3, GTPase, IMAP family member 5, Ian4, LOC100044538 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gimap5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- 50S ribosome-binding GTPase
- protein binding
- P-loop containing Nucleoside Triphosphate Hydrolases
- AIG1 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- thrombocytopenia
- hypoplasia
- anisocytosis
regulates
- lipid
- hemoglobin
- mitochondrial DNA
role in cell
- quantity
- apoptosis
- number
- differentiation
- abnormal quantity
- cellularity
- abnormal morphology
- accumulation
- abnormal number
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- mitochondrial outer membrane