Sh2d5 Gene Summary [Mouse]
Located in postsynaptic density. Orthologous to human SH2D5 (SH2 domain containing 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sh2d5 |
| Official Name | SH2 domain containing 5 [Source:MGI Symbol;Acc:MGI:2446215] |
| Ensembl ID | ENSMUSG00000045349 |
| Bio databases IDs | |
| Aliases | SH2 domain containing 5 |
| Synonyms | RGD1305952, SH2 domain containing 5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sh2d5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Src homology 2 (SH2) domain
- protein binding
- Pleckstrin homology-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- epithelial cancer
- liver cancer
- organismal death
- hepatitis B virus-related hepatocellular carcinoma
- lung adenocarcinoma
- lung adenocarcinoma formation
- stomach disorder
role in cell
- expression in
- proliferation
- binding in
- activation in
- cell rounding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sh2d5 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- postsynaptic density