Paip2b Gene Summary [Mouse]
Predicted to enable mRNA regulatory element binding translation repressor activity and poly(A) binding activity. Predicted to be involved in negative regulation of translational initiation. Predicted to be active in cytoplasm. Is expressed in embryo. Orthologous to human PAIP2B (poly(A) binding protein interacting protein 2B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Paip2b |
| Official Name | poly(A) binding protein interacting protein 2B [Source:MGI Symbol;Acc:MGI:2386865] |
| Ensembl ID | ENSMUSG00000045896 |
| Bio databases IDs | |
| Aliases | poly(A) binding protein interacting protein 2B |
| Synonyms | poly(A) binding protein interacting protein 2B, RGD1307930 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Paip2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ataxin-2 C-terminal region
- nucleic acid binding translation repressor
- poly(A) binding protein
- protein binding
- translation regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Paip2b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of translational initiation
- negative regulation of translation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- translation repressor activity
- translation repressor activity, nucleic acid binding